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陳鴻震
 陳鴻震老師
  • 職稱:講座教授兼生科院院長
  • 學歷: PhD, Pathology, Cornell University, NY, USA
  • 辦公室: 傳醫乙棟 R608 室
  • 電話: 886-2-28267200 (院長室); 886-2-28267123 (辦公室); 886-2-28267000#5653 (實驗室)
  • Email:  hcchen1029@ym.edu.tw
研究方向--
1.細胞有絲分裂之調控
2.中間絲細胞骨架之調控
3.細胞移動與腫瘤轉移
4.細胞附著及生長因子對細胞功能之調節
研究著作

Leu, C.-M., Hsu, W.-H., Lin, W.-Y., and Chen, H.-C.* (2016). Adducin family proteins possess different nuclear export potential. (in submission)

 

Kao, S.-L., Chen, C.-.L., Pan, Y.-R., and Chen, H.-C.* (2016). Biogenesis of podosome rosettes through fission. (in revision)

 

Chen CH, Chang WH, Su KY, Ku WH, Chang GC, Hong QS, Hsiao YJ, Chen HC, Chen HY, Wu R, Yang PC, Chen JJ, Yu SL.* (2016). HLJ1 is an endogenous Src inhibitor suppressing cancer progression through dual mechanisms. Oncogene 35:5674-5685.

 

Chen, C.-L., Wang, S.-H., Chan, P.-C., and Chen, H.-C.* (2016). Phosphorylation of E-cadherin at threonine 790 by protein kinase Cd suppresses the function of E-cadherin. Oncotarget 7: 37260-37276.

 

Tsai, W.-C., Chen, C.-L., and Chen, H.-C.* (2015). Protein tyrosine phosphatase SHP2 promotes invadopodia formation through suppression of Rho signaling. Oncotarget 6:23845-23856.

 

Chang, C.-H., Chan, P.-C., Li, J.-R., Chen, C.-J., Shieh, J.-J., Fu, Y.-C., Chen, H.-C.,* and Wu, M-.J.* (2015). Gab1 is essential for membrane translocation, activity and integrity of mTORCs after EGF stimulation in urothelial cell carcinoma. Oncotarget 6:1478-1489.

 

 Chan, P.-C. Hsu, R. Y. C., Liu, C.-W., Lai, C.-C., and Chen, H.-C.* (2014). Adducin-1 is essential for mitotic spindle assembly through its interaction with myosin-X. Journal of Cell Biology 204:19-28. (highlighted article)

 

 Pan., Y.-R., Tseng, W.-S., Chang, P.-W., and Chen, H.-C.* (2013). Phosphorylation of moesin by Jun N-terminal kinase is important for podosome rosette formation in Src-transformed fibroblasts. Journal of Cell Science 126:5670-5680. (cover article)

 

Hsieh, Y.-T., Chou, M.–M., Chen, H.-C.,* and Tseng, J.-J.* (2013). IMP1 promotes choriocarcinoma cell migration and invasion through novel effectors RSK2 and PPME1. Gynecological Oncology131: 182-190.

 

Pan, Y.-R., Cho, K.-H., Lee, H.-H., Chang, Z.-F., and Chen, H.-C.* (2013). Protein tyrosine phosphatase SHP2 suppresses podosome rosette formation in Src-transformed fibroblasts. Journal of Cell Science 126:(2) 657-666.

 

Chan, P.-C. and Chen, H.-C.* (2012). P120RasGAP-medaited activation of c-Src is critical for oncogenic Ras to induce tumor invasion. Cancer Research 72: 2405-2415.

 

Pan, Y.-R., Chen, C.-L., and Chen, H.-C.* (2011). FAK is required for the assembly of podosome rosettes. Journal of Cell Biology 195: 113-129.

 

Chen, C.-L., Lin, Y.-P., Lai, Y.-C., and Chen, H.-C.* (2011). a-Adducin translocates to the nucleus upon loss of cell-cell adhesions. Traffic 12: 1327-1340.

 

Lu, Y.-C. and Chen, H.-C.* (2011). Involvement of lipid rafts in adhesion-induced activation of Met and EGFR. Journal of Biomedical Science 18:78.

 

Chen, T.-H., Chan, P.-C., Chen, C.-L., and Chen, H.-C.* (2011). Phosphorylation of focal adhesion kinase on tyrosine 194 by Met leads to its activation through relief of autoinhibition. Oncogene 30: 153-166.

 

Chan, P.-C., Sudhakar, J. N., Lai, C.-C., and Chen, H.-C.* (2010). Differential phosphorylation of the docking protein Gab1 by c-Src and the hepatocyte growth factor receptor regulates different aspects of cell functions. Oncogene 29: 698-710.

 

Chen, C.-L., Chan, P.-C., Wang, S.-H., Pan, Y.-R., and Chen, H.-C.* (2010). Elevated expression of protein kinase Cd induces cell scattering upon serum deprivation. Journal of Cell Science 123: 2901-2913. (highlighted article)

 

Lee, W.-C., Chen, H.-C., Wang, C.-Y., Lin, P.-Y., Ou, T.-T., Chen, C.-C., Wen, M.-C., Wang, J., and Lee, H.-J.* (2010). Cilostazol ameliorates nephropathy in type I diabetic rats involving in oxidative stress and regulation of TGFb and NFkB. Biosci. Biotechnol. Biochem. 74: 1355-1361.

 

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